What is caffeine citrate used for?
Caffeine citrate, sold under the brand name Cafcit among others, is a medication used to treat a lack of breathing in premature babies. Specifically it is given to babies who are born at less than 35 weeks or weigh less than 2 kilograms (4. Caffeine citrate is a central stimulant agent: it inhibits adenosine receptors, affects release, turnover, and levels of several other transmitters, including biogenic amines (dopamine, noradrenalin, serotonin), acetylcholine, and excitatory and inhibitory amino acids.Caffeine is the most commonly used medication for treatment of apnea of prematurity. Its effect has been well established in reducing the frequency of apnea, intermittent hypoxemia, and extubation failure in mechanically ventilated preterm infants.To avoid unnecessarily prolonging admissions, stop caffeine at 35 weeks PMA unless the baby has ongoing apnoea. Rapid infusion of caffeine citrate may precipitate cardiac arrhythmias. Clearance of caffeine is increased by phenytoin and phenobarbitone.Cafcit (caffeine citrate) is a central nervous system stimulant used to treat breathing problems in premature infants. Cafcit is available in generic form.
What is another name for caffeine citrate?
Caffeine citrate is the generic name for the medicine, Cafcit® (KAF sit). Caffeine citrate can help to keep a premature infant from having periods of apnea (AP-nee-uh). This is when a baby stops breathing for a short time. The medicine works by stimulating the part of the brain that controls breathing. Caffeine citrate injection is used to treat short-term apnea of prematurity when premature babies (infants between 28 and 32 weeks gestational age) stop breathing. Apnea of prematurity is caused by the baby’s breathing centers not being fully developed.From experimental research it has become clear the caffeine administration acutely raises BP, but tolerance to this effect develops rapidly and heavy coffee drinkers are less likely to show a BP response after caffeine intake (Robertson et al 1981; Ammon et al 1983; Myers 1988).Caffeine administration affects the functioning of the cardiovascular, respiratory, renal, and nervous systems.How does caffeine affect blood pressure? Caffeine may cause a brief rise in your blood pressure, even if you don’t have high blood pressure. This short-term spike in blood pressure happens mainly in people who don’t drink caffeine often, rather than in those who do.The researchers noted that caffeine is believed to cause blood vessels in the uterus and placenta to constrict, which could reduce the blood supply to the fetus and inhibit growth.
What class of drug is caffeine citrate?
Caffeine citrateProduct ingredient for Caffeine Caffeine is a drug of the methylxanthine class used for a variety of purposes, including certain respiratory conditions of the premature newborn, pain relief, and to combat drowsiness. Caffeine is similar in chemical structure to Theophylline and Theobromine. Chemistry. The most common names for caffeine are 3,7-dihydro-1,3,7-trimethyl-1h-purine-2,6-dione and 1,3,7-trimethylxanthine. They are very similar and differ only by the presence of methyl groups in two positions of the chemical structure.
What kind of laxative is caffeine?
Still, according to the International Foundation for Functional Gastrointestinal Disorders (IFFGD), excessive consumption of any caffeinated drink may cause loose stools or diarrhea. And caffeine within coffee can act as a stimulant, which might induce bile production that increases bowel movements. Drinking caffeine promotes the release of noradrenaline and norepinephrine which can increase heart rate and blood pressure in some individuals. For most people this is well tolerated, but for others it may lead to palpitations or extra beats from the heart.Variations in caffeine metabolism exist, and some studies indicate that consuming as low as 100 to 200 mg of caffeine daily can prompt pregnancy complications. Common side effects include subfertility, intrauterine growth retardation, low birth weight, and spontaneous abortion [13].Adverse effects The common transient side effects attributed to caffeine include tachycardia, hypertension, tremors, vomiting and rarely opisthotonus, hyperglycemia, hypokalemia, etc.Caffeine can also have a negative impact on the brain. Some people might experience increased levels of anxiety or insomnia. It can also increase blood pressure and heart rate, which can be a concern for people with heart disease.
How to give IV caffeine citrate?
The recommended dose regimen in previously untreated infants is a loading dose of 20 mg caffeine citrate per kg body weight administered by slow intravenous infusion over 30 minutes, using a syringe infusion pump or other metered infusion device. CAFCIT should be administered with caution in infants with impaired renal or hepatic function. Serum concentrations of caffeine should be monitored and dose administration of CAFCIT should be adjusted to avoid toxicity in this population. See CLINICAL PHARMACOLOGY, Elimination and Special Populations.Caffeine is possibly unsafe when used for a long time or in doses over 400 mg daily. Caffeine can cause insomnia, nervousness, restlessness, nausea, increased heart rate, and other side effects. Larger doses might cause headache, anxiety, and chest pain.Cafcit (caffeine citrate) is a central nervous system stimulant used to treat breathing problems in premature infants. Cafcit is available in generic form.Caffeine is becoming increasingly popular among consumers worldwide due to its stimulating properties, which help promote brain function, particularly the central nervous system, increase alertness and awakening, reduce drowsiness, and make you feel refreshed, attentive, and fatigue-free.