Can theophylline be taken with coffee?
Using these medications together may increase some of the side effects of theophylline. This can cause nausea, vomiting, insomnia, tremors, restlessness, uneven heartbeats, and seizure (convulsions). Avoid drinks or foods that contain caffeine, such as coffee, tea, cola, and chocolate. Theophylline has been supplanted by the other classes of medication because it: • Has relatively weak bronchodilating prop- erties • Has no clinically important anti-inflam- matory properties • Is difficult to use because of its numerous drug interactions, the need to monitor serum levels, and its low therapeutic-to- .The pharmacodynamic effects of these two drugs are extremely similar. Caffeine is more useful for targeting the brain (e. Theophylline is more useful for targeting the visceral organs (e.Theophylline has been reported to cause disturbance of sleep in patients unaccustomed to this drug (8,16). However, in patients with nocturnal asthma this condition is improved by theophylline and for that reason they may sleep better during treatment with this drug than without it.Patients taking theophylline should avoid medications containing caffeine when possible. Patients may also need to limit their intake of caffeine-containing beverages or foods (e.
Why is theophylline high risk?
As with other methylxanthines, theophylline toxicity can lead to gastrointestinal distress, insomnia, and tremor. Reports also exist of severe nausea and vomiting, cardiac arrhythmias, hypotension, and convulsions, more commonly in cases of overdosage.Drinking or eating foods high in caffeine, like coffee, tea, cocoa, and chocolate, may increase the side effects caused by theophylline. Avoid large amounts of these substances while you are taking theophylline.An antidote to theophylline is not available, so treatment consists of gastrointestinal decontamination and alleviation of signs and symptoms.As with other methylxanthines, theophylline toxicity can lead to gastrointestinal distress, insomnia, and tremor. Reports also exist of severe nausea and vomiting, cardiac arrhythmias, hypotension, and convulsions, more commonly in cases of overdosage.
Is theophylline present in tea?
Theophylline is found in black tea and to a lesser extent in green coffee, cocoa cotyledon and dried mate. Theophylline is synthesized on an industrial scale and is used principally in pharmaceutical preparations. Per-caput daily intake of theophylline from black tea in the USA has been estimated to be 0. Trace amounts of theophylline are naturally present in tea, coffee, chocolate, yerba mate, guarana, and kola nut.Which Tea Contains the Most Theophylline? There is more theophylline in black tea than in green tea and other types of tea, but this alkaloid isn’t exclusive to Camellia sinensis. In fact, it’s found in small quantities in everything from cacao to coffee.
Who cannot take theophylline?
Many of these medications treat conditions for which theophylline is not advised, including gastroesophageal reflux disease (GERD), renal dysfunction, seizure disorders, and tachyarrhythmias. Patients should not consume excessive caffeine while taking theophylline, and they should avoid guarana. At the steady-state evaluation, theophylline significantly increased resting heart rate (HR) by 42%, mean 24-hour HR by 31% and minimal 24-hour HR by 34%.The risk or severity of seizure can be increased when Bupropion is combined with Theophylline. The metabolism of Theophylline can be decreased when combined with Buspirone.Prior exposure to caffeine was associated with a statistically significant reduction in the total amount of theophylline required to produce seizures and caused theophylline concentrations at all sampling sites to be significantly lower than in controls.Among these favorable actions of theophylline are reduction in dyspnea,7 enhanced respiratory muscle function,8 and improved cardiovascular performance.
What are signs of theophylline toxicity?
Consequences of theophylline intoxication include metabolic disturbances (hypokalemia, hyperglycemia, and metabolic acidosis), nausea, vomiting, and, in severe cases, seizures, cardiac arrhythmias, and death. The present study demonstrates small but significant deteriorations in lung function, PaCO2, exercise performance, symptoms and auscultation, and two indices of overall dyspnea 2 days after theophylline therapy withdrawal.