What is theophylline in tea?
The effects of caffeine are complemented by another compound first found in tea, theophylline. While caffeine is primarily active in the brain and muscles, theophylline has general anti-inflammatory properties, and stimulates the respiratory system, heart and kidneys. Which Tea Contains the Most Theophylline? There is more theophylline in black tea than in green tea and other types of tea, but this alkaloid isn’t exclusive to Camellia sinensis. In fact, it’s found in small quantities in everything from cacao to coffee.Theophylline is found in black tea and to a lesser extent in green coffee, cocoa cotyledon and dried mate. Theophylline is synthesized on an industrial scale and is used principally in pharmaceutical preparations.Tea contains 4 substances that have stimulating effects on your brain. The best known is caffeine, a potent stimulant that you can also get from coffee, soft drinks, and energy drinks. Tea also contains two substances related to caffeine: theobromine and theophylline.
What are the positive effects of theophylline?
Among these favorable actions of theophylline are reduction in dyspnea,7 enhanced respiratory muscle function,8 and improved cardiovascular performance. Theophylline is used to prevent and treat wheezing, shortness of breath, and chest tightness caused by asthma, chronic bronchitis, emphysema, and other lung diseases. It relaxes and opens air passages in the lungs, making it easier to breathe.Theophylline relaxes the smooth muscles located in the bronchial airways and pulmonary blood vessels. It also reduces the airway responsiveness to histamine, adenosine, methacholine, and allergens.Theophylline has been reported to cause disturbance of sleep in patients unaccustomed to this drug (8,16). However, in patients with nocturnal asthma this condition is improved by theophylline and for that reason they may sleep better during treatment with this drug than without it.Mechanistically, theophylline acts as a phosphodiesterase inhibitor, adenosine receptor blocker, and histone deacetylase activator. Theophylline is marketed under several brand names such as Uniphyl and Theochron, and it is indicated mainly for asthma, bronchospasm, and COPD.The present study demonstrates small but significant deteriorations in lung function, PaCO2, exercise performance, symptoms and auscultation, and two indices of overall dyspnea 2 days after theophylline therapy withdrawal.
Who cannot take theophylline?
Many of these medications treat conditions for which theophylline is not advised, including gastroesophageal reflux disease (GERD), renal dysfunction, seizure disorders, and tachyarrhythmias. Patients should not consume excessive caffeine while taking theophylline, and they should avoid guarana. Drinking or eating foods high in caffeine, like coffee, tea, cocoa, and chocolate, may increase the side effects caused by theophylline. Avoid large amounts of these substances while you are taking theophylline.Theophylline is found in black tea and to a lesser extent in green coffee, cocoa cotyledon and dried mate. Theophylline is synthesized on an industrial scale and is used principally in pharmaceutical preparations. Per-caput daily intake of theophylline from black tea in the USA has been estimated to be 0.Theophylline is found in black tea and to a lesser extent in green coffee, cocoa cotyledon and dried mate. Theophylline is synthesized on an industrial scale and is used principally in pharmaceutical preparations. Per-caput daily intake of theophylline from black tea in the USA has been estimated to be 0.Theophylline Description The molecular formula of anhydrous theophylline is C7H8N4O2 with a molecular weight of 180. Each extended-release tablet for oral administration contains 400 of anhydrous theophylline. Inactive Ingredients: cetostearyl alcohol, hydroxyethyl cellulose, magnesium stearate, povidone, and talc.
Is theophylline better than caffeine?
The pharmacodynamic effects of these two drugs are extremely similar. Caffeine is more useful for targeting the brain (e. Results. Caffeine, at these doses, impaired or suppressed locomotion in several paradigms. However, theophylline was less potent than caffeine at suppressing motor parameters, and even stimulated locomotion. Both drugs induced corticosterone release, however caffeine was more efficacious at intermediate doses.The pharmacodynamic effects of these two drugs are extremely similar. Caffeine is more useful for targeting the brain (e. Theophylline is more useful for targeting the visceral organs (e.
What are the benefits of theophylline?
Theophylline belongs to a group of medicines known as bronchodilators. Bronchodilators are medicines that relax the muscles in the bronchial tubes (air passages) of the lungs. They relieve cough, wheezing, shortness of breath, and troubled breathing by increasing the flow of air through the bronchial tubes. Abstract. Doxofylline, which differs from theophylline in containing the dioxalane group at position 7, has comparable efficacy to theophylline in the treatment of respiratory diseases, but with an improved tolerability profile and a favorable risk-to-benefit ratio.
What are the side effects of theophylline?
As with other methylxanthines, theophylline toxicity can lead to gastrointestinal distress, insomnia, and tremor. Reports also exist of severe nausea and vomiting, cardiac arrhythmias, hypotension, and convulsions, more commonly in cases of overdosage. Common side effects include nausea or vomiting, headache, and trouble sleeping. Many factors can affect the levels of theophylline in your body, including your dose, how you take the medicine, and other medicines you take. Your health care provider may monitor your theophylline levels.