How many hours should I wait between aspirin and ibuprofen?
The Food and Drug Administration recommends that you wait at least 8 hours after taking ibuprofen to take an immediate-relief aspirin or that you wait 30 minutes after taking aspirin to take ibuprofen. They also recommend consulting your doctor for more personalized information on how drugs can affect you. The FDA suggests that if you are taking an immediate-release aspirin with a low dosage, ibuprofen should only be taken at least 30 minutes after and at least 8 hours before the next dose of aspirin.Aspirin stops your body making prostaglandins and this lowers the pain and reduces swelling and high temperature. When will I feel better? You should start to feel better 20 to 30 minutes after taking aspirin.The Food and Drug Administration recommends that you wait at least 8 hours after taking ibuprofen to take an immediate-relief aspirin or that you wait 30 minutes after taking aspirin to take ibuprofen. They also recommend consulting your doctor for more personalized information on how drugs can affect you.No, ibuprofen does not have aspirin in it. Some combination medications will have two pain relievers together, but usually not ibuprofen and aspirin combined. Be sure to read labels carefully, especially those on over-the-counter cough and cold medicines.
What is stronger, aspirin or ibuprofen?
Determining whether aspirin or ibuprofen is the better option for you depends partly on your health history. All NSAIDs are similarly effective in relieving mild pain. But while they both work well for minor pain, ibuprofen works better for moderate pain. It’s safe to take aspirin as a painkiller with paracetamol or codeine. But do not take aspirin with ibuprofen or naproxen without talking to a doctor. Aspirin, ibuprofen and naproxen belong to the same group of medicines called non-steroidal anti-inflammatory drugs (NSAIDs).Nonprescription ibuprofen (Advil, Motrin) treats fever, common colds, and minor aches and pains. In general, ibuprofen works better to relieve pain and is less likely to cause stomach irritation compared to aspirin. However, aspirin may be the safer choice for people with a history of cardiovascular disease.Taking low-dose aspirin with painkillers If you take them together, aspirin plus ibuprofen or naproxen may increase your chances of side effects like stomach irritation.
What cannot be mixed with ibuprofen?
Taking ibuprofen with other painkillers Do not take ibuprofen at the same time as other non-steroidal anti-inflammatory drugs (NSAIDs), such as naproxen or aspirin. This can increase the risk of serious side effects like stomach ulcers. Description. Ibuprofen is a nonsteroidal anti-inflammatory drug (NSAID) used to treat mild to moderate pain, and helps to relieve symptoms of arthritis (osteoarthritis, rheumatoid arthritis, or juvenile arthritis), such as inflammation, swelling, stiffness, and joint pain.
What are the side effects of mixing aspirin & ibuprofen?
Aspirin, ibuprofen and naproxen all belong to the same group of medicines called non-steroidal anti-inflammatory drugs (NSAIDs). If you take them together, aspirin plus ibuprofen or naproxen may increase your chances of side effects like stomach irritation. Taking aspirin and other painkillers Aspirin, ibuprofen and naproxen belong to the same group of medicines called non-steroidal anti-inflammatory drugs (NSAIDs). If you take them together, aspirin and ibuprofen or naproxen may increase the chance of you getting side effects like stomach ache.Naproxen. Naproxen (Aleve) is one of the most powerful anti-inflammatory pain reliever available without a prescription. It is especially effective for sprains, sunburns and arthritis. Naproxen usually lasts longer than other over-the-counter pain relievers.
How long does aspirin stay in your system?
Aspirin will generally stay in your system for up to 10 days because it works on platelets, and platelets have a life of 10 days. However, the exact length of time aspirin stays in your system can vary based on whether or not the tablet is coated, the dose taken, and the dosage form. Enteric coating of aspirin significantly delays its absorption. The plasma half-life of aspirin is only 20 minutes; however, because platelets cannot generate new COX, the effects of aspirin last for the duration of the life of the platelet (≈10 days).How long does it take for aspirin to work? Aspirin is digested and absorbed quickly into the blood and starts acting on platelets right away. Platelets stop clumping within 60 minutes of taking aspirin. Platelets can’t easily recover their ability to clot once they encounter aspirin.
How long does ibuprofen stay in your system?
A regular 400mg dose of Ibuprofen will be eliminated from your system in about 10-24 hours. It’s not habit-forming, so there is a low potential to develop painkiller addiction. But, some people can become psychologically addicted to Ibuprofen. The 3-3-3 rule refers to taking 600 mg of ibuprofen (typically 3 tablets of 200 mg), 3 times a day, for no more than 3 days. This approach is intended to help reduce inflammation—one of the most common causes of dental pain—by keeping a steady level of medication in your system.Medically reviewed by Carmen Pope, BPharm. Last updated on July 18, 2025. Ibuprofen starts working within 20 to 30 minutes after taking it, with maximum pain relief effects occurring within 1 to 2 hours.