Does theacrine cause anxiety?
The initial two-part pilot study involving human subjects administered theacrine at 200 or 400 mg in 9 subjects over a 7-day period. Researchers noted moderate to large effect sizes for energy, fatigue, concentration, anxiety, motivation to exercise, and libido with the 200-mg dose [7]. Pharmacokinetics. Theacrine has half-life of 30 to 33 hours.
Does theacrine affect sleep?
The present study provides evidence to suggest theacrine consumption does not disrupt subsequent sleep in the same manner as caffeine. Signs of Consuming Too Much Caffeine increased heart rate.
Does theacrine increase dopamine?
Theacrine acts as an adenosine receptor antagonist to play a role in the locomotor activation and fatigue reduction. Theacrine regulates brain glucose metabolism, inhibits phosphodiesterases and restores the levels of 5-HTP and dopamine to improve cognitive capacity. Theacrine activates dopamine receptors D1 and D2, supporting dopaminergic signaling. In addition to the dopamine boosting effects, TeaCrine is also thought to inhibit adenosinergic activity.
Is TeaCrine the same as theacrine?
TeaCrine® is a nature-identical, chemically equivalent bioactive version of theacrine. Theacrine is a purine alkaloid that is converted from caffeine by hydration, oxidation and methylation [1] and it is thought to influence the central nervous system as a neuroactive ingredient. Studies have shown that TeaCrine’s half-life is longer than caffeine, enhancing sustained energy for 4-8 hours, as opposed to caffeine’s at 1-2 hours. Studies have shown that TeaCrine does help increase time to exhaustion, delay muscle fatigue and improve athletic performance [R].