November 2025

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What does caffeine citrate do?

What does caffeine citrate do? caffeine citrate injection is used to treat short-term apnea of prematurity when premature babies (infants between 28 and 32 weeks gestational age) stop breathing. Apnea of prematurity is caused by the baby’s breathing centers not being fully developed. Caffeine citrate (cafcit) is a medication that works well for treating breathing

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Why give NICU babies caffeine?

Why give NICU babies caffeine? Caffeine is the most commonly used medication for treatment of apnea of prematurity. Its effect has been well established in reducing the frequency of apnea, intermittent hypoxemia, and extubation failure in mechanically ventilated preterm infants. Caffeine has various dose-related side effects on different systems. Accidental administration of high dose caffeine

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What does caffeine do for neonates?

What does caffeine do for neonates? Caffeine is the most commonly used medication for treatment of apnea of prematurity. Its effect has been well established in reducing the frequency of apnea, intermittent hypoxemia, and extubation failure in mechanically ventilated preterm infants. Description. Caffeine citrate injection is used to treat short-term apnea of prematurity when premature

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What is the mechanism of action of caffeine in apnea?

What is the mechanism of action of caffeine in apnea? The exact mechanism of action of caffeine in treating apnea related to prematurity is unknown, however, there are several proposed mechanisms, including respiratory center stimulation in the central nervous system, a reduced threshold to hypercapnia with increased response, and increased consumption of oxygen, among .

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How to give caffeine in neonates?

How to give caffeine in neonates? The recommended loading dose of caffeine citrate is 20 mg/kg orally or intravenously followed by 5 mg/kg daily oral (or IV over 30 minutes) maintenance doses. The recommended loading dose of theophylline is 5–6 mg/kg, followed by maintenance doses of 2–6 mg/kg/day divided into two or three doses. Intravenous

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